27/05/2017
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Health, Biology and Medicine>Medical Biotechnology Nanotechnology>
Health, Biology and Medicine>Cell Technology/Cell Biology >
Health, Biology and Medicine>Cell Therapy >
Cell therapy for Corneal Injuries
Treatment of limbal stem cell deficiency (LSCD)




Our current technique for autologous limbal transplantation
• Accurately diagnose LSCD (erroneous diagnosis may subject the patient to unnecessary surgeries)
• Culturing the donor tissue (1x2 mm) on amniotic membrane
• Proliferation of limbal stem cells for 14 days (3x3 cm)
• Transplantation





Limbal Stem Cell culture and Transplantation For Corneal Injuries

There is a relation between the subpopulation of stem cells located in the limbal region and the maintenance of a healthy functional corneal epithelium

• What is LSCD?
A pathological state in which limbal epithelial stem cells are destroyed or become dysfunctional that is called limbal stem cell deficiency (LSCD).

• Which diseases are accompanied with LSCD ?

chemical burns, Stevens Johnson syndrome, aniridia, peripheral keratitis, severe limbitis, etc.

• Symptoms of LSCD?

 Patients with LSCD suffer from a severe loss of vision and annoying photophobia, and cannot be corrected by conventional PKP.

• What is the choice treatment?

    transplantation

• The improvement percent of vision after treatment  ?

 more than 60 % in successful transplantation and culturing .

• Is there any complication after cultivated limbal stemcell transplantation
?

No

• Need of Hospitalization?

yes . just for biopsy and transplantation .

• The perfect age?

Recommended  for patients older than 9.
Our offerings :
Bilateral or Multilateral Research Cooperation
Clinical Services
Training

The ACECR affiliate in charge:
Reproductive Biomedicine Stem Cell Biology and Technology (Royan Institute)
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